McKenzie holds a BA in film studies from Yale University and an MFA in painting from the University of Michigan. McKenzie has exhibited her paintings nationally, including shows with the Walker Art Center in Minneapolis, the Carnegie Museum of Art in Pittsburgh, the Yale School of Architecture, the New Mexico Museum of Art in Santa Fe, the Museum of Contemporary Art Denver, the Aspen Art Museum, and the Indianapolis Museum of Contemporary Art, among other venues. In 2012, McKenzie received a Joan Mitchell Painters and Sculptors Grant, and in 2019, she was awarded the 10th Alexander Rutsch Award for Painting. In Spring 2021, McKenzie received the Marion International Fellowship for the Visual and Performing Arts to support her prison architecture series. When she is not in the studio, McKenzie helps to run Tilt West, a Denver based arts and culture nonprofit, and she teaches visual art through the University of Denver Prison Arts Initiative (DU PAI).